SAFETY DATA SHEETS
According to the UN GHS revision 10
SECTION 1: Identification
1.1 GHS Product identifier
| Product name |
2,2'-iminodiethanol |
|---|
1.2 Other means of identification
| Product number |
- |
|---|---|
| Other names |
DEA; 2,2'-Azanediyldiethanol; Ethanol, 2,2‘-iminobis- |
1.3 Recommended use of the chemical and restrictions on use
| Identified uses |
Industrial and scientific research use. |
|---|---|
| Uses advised against |
no data available |
1.4 Supplier's details
| Company |
chemicalbook |
|---|---|
| Address |
507, building 1, Huihuang international, Shangdi 10th Street, Haidian District, Beijing |
| Telephone |
+86-10-69703845 |
1.5 Emergency phone number
| Emergency phone number |
+86-13121892008 |
|---|---|
| Service hours |
Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours). |
SECTION 2: Hazard identification
2.1 Classification of the substance or mixture
Acute toxicity - Category 4, Oral
Skin irritation, Category 2
Serious eye damage, Category 1
Specific target organ toxicity – repeated exposure, Category 2
2.2 GHS label elements, including precautionary statements
| Pictogram(s) |
|
|---|---|
| Signal word |
Danger |
| Hazard statement(s) |
H302 Harmful if swallowed H315 Causes skin irritation H318 Causes serious eye damage H373 May cause damage to organs through prolonged or repeated exposure |
| Precautionary statement(s) | |
| Prevention |
P264 Wash ... thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/... P260 Do not breathe dust/fume/gas/mist/vapours/spray. |
| Response |
P301+P317 IF SWALLOWED: Get medical help. P330 Rinse mouth. P302+P352 IF ON SKIN: Wash with plenty of water/... P321 Specific treatment (see ... on this label). P332+P317 If skin irritation occurs: Get medical help. P362+P364 Take off contaminated clothing and wash it before reuse. P305+P354+P338 IF IN EYES: Immediately rinse with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P317 Get medical help. P319 Get medical help if you feel unwell. |
| Storage |
none |
| Disposal |
P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal. |
2.3 Other hazards which do not result in classification
no data available
SECTION 3: Composition/information on ingredients
3.1 Substances
| Chemical name | Common names and synonyms | CAS number | EC number | Concentration |
|---|---|---|---|---|
| 2,2'-iminodiethanol | 2,2'-iminodiethanol | 111-42-2 | 203-868-0 | 100% |
SECTION 4: First-aid measures
4.1 Description of necessary first-aid measures
If inhaled
Fresh air, rest.
Following skin contact
Remove contaminated clothes. Rinse skin with plenty of water or shower.
Following eye contact
First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.
Following ingestion
Rinse mouth. Give one or two glasses of water to drink. Refer for medical attention . Rest.
4.2 Most important symptoms/effects, acute and delayed
Irritation of eyes and skin. Breathing vapors may cause coughing, a smothering sensation, nausea, headache. (USCG, 1999)
4.3 Indication of immediate medical attention and special treatment needed, if necessary
Immediate first aid: Ensure that adequate decontamination has been carried out. If patient is not breathing, start artificial respiration, preferably with a demand valve resuscitator, bag-valve-mask device, or pocket mask, as trained. Perform CPR if necessary. Immediately flush contaminated eyes with gently flowing water. Do not induce vomiting. If vomiting occurs, lean patient forward or place on the left side (head-down position, if possible) to maintain an open airway and prevent aspiration. Keep patient quiet and maintain normal body temperature. Obtain medical attention. /Organic bases/Amines and related compounds/
SECTION 5: Fire-fighting measures
5.1 Suitable extinguishing media
Wear self contained breathing apparatus for fire fighting if necessary.
5.2 Specific hazards arising from the chemical
Special Hazards of Combustion Products: Irritating vapors are generated when heated. (USCG, 1999)
5.3 Special protective actions for fire-fighters
Use water spray, powder, foam, carbon dioxide.
SECTION 6: Accidental release measures
6.1 Personal precautions, protective equipment and emergency procedures
Personal protection: filter respirator for organic gases and particulates adapted to the airborne concentration of the substance. Sweep spilled substance into covered sealable containers. If appropriate, moisten first to prevent dusting. Then store and dispose of according to local regulations.
6.2 Environmental precautions
Personal protection: filter respirator for organic gases and particulates adapted to the airborne concentration of the substance. Sweep spilled substance into covered sealable containers. If appropriate, moisten first to prevent dusting. Then store and dispose of according to local regulations.
6.3 Methods and materials for containment and cleaning up
Personal precautions, protective equipment and emergency procedures: Use personal protective equipment. Avoid breathing vapours, mist or gas. Ensure adequate ventilation. Evacuate personnel to safe areas.
SECTION 7: Handling and storage
7.1 Precautions for safe handling
NO open flames. Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
7.2 Conditions for safe storage, including any incompatibilities
Separated from strong oxidants and acids. Dry.Keep container tightly closed in a dry and well-ventilated place. Containers which are opened must be carefully resealed and kept upright to prevent leakage. Air sensitive.
SECTION 8: Exposure controls/personal protection
8.1 Control parameters
Occupational Exposure limit values
TLV: 1 mg/m3, as TWA; (skin); A3 (confirmed animal carcinogen with unknown relevance to humans).MAK: (inhalable fraction): 1 mg/m3; peak limitation category: I(1); skin absorption (H); sensitization of skin (SH); carcinogen category: 3B; pregnancy risk group: C
Biological limit values
no data available
8.2 Appropriate engineering controls
Ensure adequate ventilation. Handle in accordance with good industrial hygiene and safety practice. Set up emergency exits and the risk-elimination area.
8.3 Individual protection measures, such as personal protective equipment (PPE)
Eye/face protection
Wear safety goggles or eye protection in combination with breathing protection.
Skin protection
Protective gloves. Protective clothing.
Respiratory protection
Use local exhaust or breathing protection.
Thermal hazards
no data available
SECTION 9: Physical and chemical properties and safety characteristics
| Physical state |
Solid. Crystals (prisms) or syrupy liquid (above 82 degrees F). |
|---|---|
| Colour |
Colorless. |
| Odour |
Mild, ammonia-like odor |
| Melting point/freezing point |
27 °C. Atm. press.:1 013 hPa. |
| Boiling point or initial boiling point and boiling range |
269.9 °C. Atm. press.:1 013.25 hPa. Remarks:At and above 200 °C, decomposition can clearly be observed. |
| Flammability |
Class IIIB Combustible Liquid: Fl.P. at or above 200°F.Combustible Solid |
| Lower and upper explosion limit/flammability limit |
Lower flammable limit: 1.6% by volume (calculated); Upper flammable limit: 9.8% by volume (estimated) |
| Flash point |
176 °C. Atm. press.:1 013 hPa. |
| Auto-ignition temperature |
375 °C. Atm. press.:1 013 hPa. |
| Decomposition temperature |
no data available |
| pH |
Strong base. pH of 0.1 N aqueous solution: 11.0 |
| Kinematic viscosity |
dynamic viscosity (in mPa s) = 390.9. Temperature:30.0°C. Remarks:Calculated based on static viscosity.;dynamic viscosity (in mPa s) = 102.7. Temperature:50.0°C. |
| Solubility |
Miscible with water |
| Partition coefficient n-octanol/water |
log Pow = -2.46. Temperature:25 °C. |
| Vapour pressure |
1 hPa. Temperature:108 °C. Remarks:Measured.;0 hPa. Temperature:20 °C. Remarks:Calculated by regression (Antoine equation).;0 hPa. Temperature:25 °C. Remarks:Calculated by regression (Antoine equation). |
| Density and/or relative density |
1 095.3 kg/m3. Temperature:23.8 °C. |
| Relative vapour density |
3.6 (vs air) |
| Particle characteristics |
no data available |
SECTION 10: Stability and reactivity
10.1 Reactivity
Decomposes on burning. This produces toxic fumes. The solution in water is a medium strong base. Reacts violently with strong oxidants and strong acids. Attacks copper, zinc, aluminium and their alloys.
10.2 Chemical stability
no data available
10.3 Possibility of hazardous reactions
Combustile, when exposed to heat or flame; can react with oxidizing materials.The vapour is heavier than air.DIETHANOLAMINE is an aminoalcohol. Amines are chemical bases. They neutralize acids to form salts plus water. These acid-base reactions are exothermic. The amount of heat that is evolved per mole of amine in a neutralization is largely independent of the strength of the amine as a base. Amines may be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen is generated by amines in combination with strong reducing agents, such as hydrides. This compound is hygroscopic. It may be sensitive to exposure to air and light. This compound can react with oxidizing materials, acids, CO2, copper alloys, aluminum, zinc, galvanized iron and copper. (NTP, 1992)
10.4 Conditions to avoid
no data available
10.5 Incompatible materials
DEA (Diethanolamine) degrades in the presense of carbon dioxide to yield HEOD [3-(2-hydroxy-ethyl)oxazolidone], THEED [N,N,N,'-(2-hydroxyethyl)ethyleen-diamine] and BHEP [N,N'-bis(2-hydroxyethyl)piperazine.
10.6 Hazardous decomposition products
Special hazards arising from the substance or mixture: Carbon oxides, nitrogen oxides (NOx). Nature of decomposition products not known.
SECTION 11: Toxicological information
Acute toxicity
- Oral: LD50 - rat (male) - ca. 1 100 mg/kg bw.
- Inhalation: LC0 - rat (male/female) - 0.2 mg/L air.
- Dermal: no data available
Skin corrosion/irritation
no data available
Serious eye damage/irritation
no data available
Respiratory or skin sensitization
no data available
Germ cell mutagenicity
no data available
Carcinogenicity
Evaluation: Cancer in humans: There is inadequate evidence in humans for the carcinogenicity of diethanolamine. Cancer in experimental animals: There is sufficient evidence in experimental animals for the carcinogenicity of diethanolamine. Overall evaluation: Diethanolamine is possibly carcinogen to humans (Group 2B).
Reproductive toxicity
No information is available on the reproductive or developmental effects of diethanolamine in humans. Animal studies have reported testicular degeneration and reduced sperm motility and count from oral exposure to diethanolamine. (10)
STOT-single exposure
The substance is corrosive to the eyes.
STOT-repeated exposure
Repeated or prolonged contact may cause skin sensitization. The substance may have effects on the liver and kidneys.
Aspiration hazard
A harmful contamination of the air will not or will only very slowly be reached on evaporation of this substance at 20°C.
SECTION 12: Ecological information
12.1 Toxicity
- Toxicity to fish: LC50 - Oncorhynchus mykiss (previous name: Salmo gairdneri) - 460 mg/L - 96 h. Remarks:Analytically verified.
- Toxicity to daphnia and other aquatic invertebrates: EC50 - Ceriodaphnia dubia - 30.1 mg/L - 48 h.
- Toxicity to algae: EC50 - Pseudokirchneriella subcapitata (previous names: Raphidocelis subcapitata, Selenastrum capricornutum) - 9.5 mg/L - 72 h.
- Toxicity to microorganisms: EC10 - activated sludge, domestic - > 1 000 mg/L - 30 min. Remarks:Respiration rate.
12.2 Persistence and degradability
AEROBIC: Biodegradation of diethanolamine has been reported in many die-away tests(1-3). N-Nitrosodiethanolamine has been identified as a metabolite of diethanolamine in natural water samples and sewage(2).Media Initial Concn Incubation Time (days) % Biodegradation Reference River Water 21 mg/L 4 5 1 River Water 210 ug/L 4 55 1 River Water 21 ng/L 4 32 1 Lake Water 1.1 ppm 14 31 2 Acidic Lake Water 1.1 ppm 14 1.2 2 Sewage 1.1 ppm 14 53 2 River Water 50 ppm 10 90 3
12.3 Bioaccumulative potential
An estimated BCF of 3 was calculated in fish for diethanolamine(SRC), using a log Kow of -1.43(1) and a regression-derived equation(2). According to a classification scheme(3), this BCF suggests the potential for bioconcentration in aquatic organisms is low(SRC).
12.4 Mobility in soil
The Koc of diethanolamine has been reported as 3.97(1) and an experimental log Koc of 0.60(2). According to a classification scheme(3), these Koc values suggest that diethanolamine is expected to have very high mobility in soil. The pKa of diethanolamine is 8.96(4), indicating that this compound will exist partially in cation form in the environment and cations generally adsorb more strongly to soils containing organic carbon and clay than their neutral counterparts(5). Diethanolamine has been shown to adsorb to humic acid which may be contained in soils and sediments(6). The adsorption of diethanolamine on humic acid changed very slightly from pH 4-8, (40-45% adsorption)(6).
12.5 Other adverse effects
no data available
SECTION 13: Disposal considerations
13.1 Disposal methods
Product
The material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.
Contaminated packaging
Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.
SECTION 14: Transport information
14.1 UN Number
| ADR/RID: Not dangerous goods. (For reference only, please check.) | IMDG: Not dangerous goods. (For reference only, please check.) | IATA: Not dangerous goods. (For reference only, please check.) |
14.2 UN Proper Shipping Name
| ADR/RID: Not dangerous goods. (For reference only, please check.) | IMDG: Not dangerous goods. (For reference only, please check.) | IATA: Not dangerous goods. (For reference only, please check.) |
14.3 Transport hazard class(es)
| ADR/RID: Not dangerous goods. (For reference only, please check.) | IMDG: Not dangerous goods. (For reference only, please check.) | IATA: Not dangerous goods. (For reference only, please check.) |
14.4 Packing group, if applicable
| ADR/RID: Not dangerous goods. (For reference only, please check.) | IMDG: Not dangerous goods. (For reference only, please check.) | IATA: Not dangerous goods. (For reference only, please check.) |
14.5 Environmental hazards
| ADR/RID: No | IMDG: No | IATA: No |
14.6 Special precautions for user
no data available
14.7 Transport in bulk according to IMO instruments
no data available
SECTION 15: Regulatory information
15.1 Safety, health and environmental regulations specific for the product in question
| Chemical name | Common names and synonyms | CAS number | EC number |
|---|---|---|---|
| 2,2'-iminodiethanol | 2,2'-iminodiethanol | 111-42-2 | 203-868-0 |
| European Inventory of Existing Commercial Chemical Substances (EINECS) | Listed. | ||
| EC Inventory | Listed. | ||
| United States Toxic Substances Control Act (TSCA) Inventory | Listed. | ||
| China Catalog of Hazardous chemicals 2015 | Listed. | ||
| New Zealand Inventory of Chemicals (NZIoC) | Listed. | ||
| Philippines Inventory of Chemicals and Chemical Substances (PICCS) | Listed. | ||
| Vietnam National Chemical Inventory | Listed. | ||
| Chinese Chemical Inventory of Existing Chemical Substances (China IECSC) | Listed. | ||
| Korea Existing Chemicals List (KECL) | Listed. | ||
SECTION 16: Other information
Information on revision
| Creation Date | July 15, 2019 |
|---|---|
| Revision Date | July 15, 2019 |
Abbreviations and acronyms
- CAS: Chemical Abstracts Service
- ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
- RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
- IMDG: International Maritime Dangerous Goods
- IATA: International Air Transportation Association
- TWA: Time Weighted Average
- STEL: Short term exposure limit
- LC50: Lethal Concentration 50%
- LD50: Lethal Dose 50%
- EC50: Effective Concentration 50%
References
- IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
- HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
- IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
- eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
- CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
- ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
- ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
- Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
- ECHA - European Chemicals Agency, website: https://echa.europa.eu/
Other Information
Do NOT take working clothes home.
Any questions regarding this SDS, Please send your inquiry to sds@xixisys.com
Disclaimer: The above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any guarantee of the properties of the product. We as supplier shall not be held liable for any damage resulting from handling or from contact with the above product.