SAFETY DATA SHEETS
According to the UN GHS revision 10
SECTION 1: Identification
1.1 GHS Product identifier
| Product name |
2-chloroethanol |
|---|
1.2 Other means of identification
| Product number |
- |
|---|---|
| Other names |
CH2ClCH2OH; Ethanol, 2-chloro-; 2-CHLORETHANOL |
1.3 Recommended use of the chemical and restrictions on use
| Identified uses |
Industrial and scientific research use. |
|---|---|
| Uses advised against |
no data available |
1.4 Supplier's details
| Company |
chemicalbook |
|---|---|
| Address |
507, building 1, Huihuang international, Shangdi 10th Street, Haidian District, Beijing |
| Telephone |
+86-10-69703845 |
1.5 Emergency phone number
| Emergency phone number |
+86-13121892008 |
|---|---|
| Service hours |
Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours). |
SECTION 2: Hazard identification
2.1 Classification of the substance or mixture
Acute toxicity - Category 2, Oral
Acute toxicity - Category 1, Dermal
Acute toxicity - Category 2, Inhalation
2.2 GHS label elements, including precautionary statements
| Pictogram(s) |
|
|---|---|
| Signal word |
Danger |
| Hazard statement(s) |
H300 Fatal if swallowed H310 Fatal in contact with skin H330 Fatal if inhaled |
| Precautionary statement(s) | |
| Prevention |
P264 Wash ... thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P262 Do not get in eyes, on skin, or on clothing. P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/... P260 Do not breathe dust/fume/gas/mist/vapours/spray. P271 Use only outdoors or in a well-ventilated area. P284 [In case of inadequate ventilation] wear respiratory protection. |
| Response |
P301+P316 IF SWALLOWED: Get emergency medical help immediately. P321 Specific treatment (see ... on this label). P330 Rinse mouth. P302+P352 IF ON SKIN: Wash with plenty of water/... P316 Get emergency medical help immediately. P361+P364 Take off immediately all contaminated clothing and wash it before reuse. P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing. P320 Specific treatment is urgent (see ... on this label). |
| Storage |
P405 Store locked up. P403+P233 Store in a well-ventilated place. Keep container tightly closed. |
| Disposal |
P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal. |
2.3 Other hazards which do not result in classification
no data available
SECTION 3: Composition/information on ingredients
3.1 Substances
| Chemical name | Common names and synonyms | CAS number | EC number | Concentration |
|---|---|---|---|---|
| 2-chloroethanol | 2-chloroethanol | 107-07-3 | 203-459-7 | 100% |
SECTION 4: First-aid measures
4.1 Description of necessary first-aid measures
If inhaled
Fresh air, rest. Half-upright position. Artificial respiration may be needed. Refer for medical attention.
Following skin contact
Remove contaminated clothes. Rinse and then wash skin with water and soap. Refer for medical attention .
Following eye contact
First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.
Following ingestion
Rinse mouth. Induce vomiting (ONLY IN CONSCIOUS PERSONS!). Refer for medical attention .
4.2 Most important symptoms/effects, acute and delayed
Very toxic; probable oral lethal dose in humans is 50-500 mg/kg or between 1 teaspoon and 1 ounce for a 70 kg (150 lb.) person. Poisoning causes liver and kidney degeneration and irritates mucous membranes; it may be cumulative. Several fatal cases with brain edema and lung edema have been reported from industrial exposure by inhalation and skin contact. It is more toxic by skin contact than orally. (EPA, 1998)
4.3 Indication of immediate medical attention and special treatment needed, if necessary
Minimum/Potential Fatal Human Dose
4= very toxic: probable oral lethal dose (human) 50-500 mg/kg, between 1 teaspoon & 1 ounce for 70 kg person (150 lb).
Absorption, Distribution and Excretion
May be absorbed through the skin.
SECTION 5: Fire-fighting measures
5.1 Suitable extinguishing media
Water, alcohol foam, dry chemical, or carbon dioxide.
5.2 Specific hazards arising from the chemical
Its decomposition products will react with water or steam to produce toxic and corrosive fumes of phosgene and hydrogen chloride. Vapors are heavier than air and may flash back to a source of ignition. (EPA, 1998)
5.3 Special protective actions for fire-fighters
Use water spray, powder, alcohol-resistant foam, carbon dioxide. In case of fire: keep drums, etc., cool by spraying with water.
SECTION 6: Accidental release measures
6.1 Personal precautions, protective equipment and emergency procedures
Personal protection: complete protective clothing including self-contained breathing apparatus. Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations.
6.2 Environmental precautions
Personal protection: complete protective clothing including self-contained breathing apparatus. Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations.
6.3 Methods and materials for containment and cleaning up
1. Remove all ignition sources. 2. Ventilate area of spill or leak. 3. For small quantities, absorb on paper towels. Evaporate in a safe place (such as a fume hood). Allow sufficient time for evaporating vapors to completely clear the hood ductwork. Burn the paper in a suitable location away from combustible materials. Large quantities can be collected and atomized in a suitable combustion chamber equipped with an appropriate effluent gas cleaning device. Ethylene chlorohydrin should not be allowed to enter a confined space, such as a sewer, because of the possibility of an explosion.
SECTION 7: Handling and storage
7.1 Precautions for safe handling
NO open flames, NO sparks and NO smoking. Above 60°C use a closed system, ventilation and explosion-proof electrical equipment. Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
7.2 Conditions for safe storage, including any incompatibilities
Fireproof. Separated from strong bases, oxidants and food and feedstuffs. Dry. Well closed.
SECTION 8: Exposure controls/personal protection
8.1 Control parameters
Occupational Exposure limit values
TLV: 1 ppm as STEL; (skin); A4 (not classifiable as a human carcinogen).MAK: 6.7 mg/m3, 2 ppm; peak limitation category: II(1); skin absorption (H); pregnancy risk group: C
Biological limit values
no data available
8.2 Appropriate engineering controls
Ensure adequate ventilation. Handle in accordance with good industrial hygiene and safety practice. Set up emergency exits and the risk-elimination area.
8.3 Individual protection measures, such as personal protective equipment (PPE)
Eye/face protection
Wear safety goggles, face shield or eye protection in combination with breathing protection.
Skin protection
Protective gloves. Protective clothing.
Respiratory protection
Use ventilation, local exhaust or breathing protection.
Thermal hazards
no data available
SECTION 9: Physical and chemical properties and safety characteristics
| Physical state |
Liquid. Glycerin-like. |
|---|---|
| Colour |
Colourless. |
| Odour |
FAINT ETHEREAL ODOR |
| Melting point/freezing point |
-67.5 °C. |
| Boiling point or initial boiling point and boiling range |
128 - 130 °C. Atm. press.:1 013 hPa. |
| Flammability |
Class IIIA Combustible Liquid: Fl.P. at or above 140°F and below 200°F. |
| Lower and upper explosion limit/flammability limit |
Lower flammable limit: 4.9% by volume; Upper flammable limit: 15.9% by volume |
| Flash point |
40.56 °C. |
| Auto-ignition temperature |
425 °C. Remarks:Value from peer reviewed Database. No data available for atm. pressure. |
| Decomposition temperature |
no data available |
| pH |
no data available |
| Kinematic viscosity |
0.0343 POISE @ 20 DEG C |
| Solubility |
greater than or equal to 100 mg/mL at 66° F (NTP, 1992) |
| Partition coefficient n-octanol/water |
log Pow = -0.06. Remarks:Value from generally accepted authoritative secondary source. No data available for temperature and pH value. |
| Vapour pressure |
6.53 hPa. Temperature:20 °C. |
| Density and/or relative density |
1.197. Temperature:20 °C. |
| Relative vapour density |
2.78 (vs air) |
| Particle characteristics |
no data available |
SECTION 10: Stability and reactivity
10.1 Reactivity
Decomposes on burning. This produces toxic and corrosive gases of hydrogen chloride and phosgene. Reacts violently with oxidants. This generates fire and explosion hazard. Reacts with water and steam. This produces toxic and corrosive fumes. Reacts with strong bases. This produces ethylene oxide. This generates fire and toxic hazard.
10.2 Chemical stability
It evaporates readily at room temperature
10.3 Possibility of hazardous reactions
MODERATE, WHEN EXPOSED TO HEAT, FLAME OR OXIDIZERS.Mixing ethylene chlorohydrin in equal molar portions with any of the following substances in a closed container caused the temperature and pressure to increase: chlorosulfonic acid, ethylene diamine, and sodium hydroxide, [NFPA 1991]. Ethylenediamine reacts violently with ethylene chlorohydrin. (Lewis, R.J., Sr. 1992. Sax's Dangerous Properties of Industrial Materials, 8th Edition. New York: Van Nostrand Reinhold. pp. 1554.).
10.4 Conditions to avoid
no data available
10.5 Incompatible materials
Will react with water or steam to produce toxic & corrosive fumes .
10.6 Hazardous decomposition products
When heated to decomposition, it emits highly toxic fumes of phosgene .
SECTION 11: Toxicological information
Acute toxicity
- Oral: LD50 - rat (male/female) - 77 mg/kg bw.
- Inhalation: concentration resulting in lethal effects in 2-4 out of 6 treated rats - rat (male/female) - 32 ppm.
- Dermal: LD50 - guinea pig - 260 mg/kg bw.
Skin corrosion/irritation
no data available
Serious eye damage/irritation
no data available
Respiratory or skin sensitization
no data available
Germ cell mutagenicity
no data available
Carcinogenicity
A4; Not classifiable as a human carcinogen.
Reproductive toxicity
no data available
STOT-single exposure
The substance is severely irritating to the eyes and respiratory tract. The substance may cause effects on the central nervous system, cardiovascular system, kidneys and liver. This may result in cardiac disorders, low blood pressure, kidney impairment, liver impairment and respiratory failure. Exposure could cause death.
STOT-repeated exposure
no data available
Aspiration hazard
A harmful contamination of the air can be reached very quickly on evaporation of this substance at 20°C.
SECTION 12: Ecological information
12.1 Toxicity
- Toxicity to fish: LC50 - Gambusia affinis - 15.2 mg/L - 96 h.
- Toxicity to daphnia and other aquatic invertebrates: EC50 - Daphnia magna - 212 mg/L - 48 h.
- Toxicity to algae: EC50 - Desmodesmus subspicatus (previous name: Scenedesmus subspicatus) - 5.6 mg/L - 72 h.
- Toxicity to microorganisms: EC 20 - activated sludge, industrial - > 2 000 mg/L - 30 min. Remarks:Respiration rate.
12.2 Persistence and degradability
2-Chloroethanol is readily biodegradable in screening tests and biological treatment simulations using sewage and activated sludge inocula(1-6). Various investigators have obtained the following results in percent of theoretical BOD in screening tests using sewage inocula: 57% in 20 days(1); 50% in 10 days(2); and 87% in 10 days(3). The results of these screening tests indicate that acclimation is important in the biodegradation process.
12.3 Bioaccumulative potential
Using the log octanol/water partition coefficient for 2-chloroethanol, 0.03(1), one can estimate a BCF of 0.62 using a recommended regression equation(2,SRC). Therefore, 2-chloroethanol would not be expected to bioconcentrate in aquatic organisms.
12.4 Mobility in soil
The Koc for 2-chloroethanol estimated from molecular structure is 1.33(1). According to a suggested classification scheme, a Koc of this magnitude indicates that 2-chloroethanol will exhibit very high mobility in soil(2).
12.5 Other adverse effects
no data available
SECTION 13: Disposal considerations
13.1 Disposal methods
Product
The material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.
Contaminated packaging
Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.
SECTION 14: Transport information
14.1 UN Number
| ADR/RID: UN1135 (For reference only, please check.) | IMDG: UN1135 (For reference only, please check.) | IATA: UN1135 (For reference only, please check.) |
14.2 UN Proper Shipping Name
| ADR/RID: ETHYLENE CHLOROHYDRIN (For reference only, please check.) | IMDG: ETHYLENE CHLOROHYDRIN (For reference only, please check.) | IATA: ETHYLENE CHLOROHYDRIN (For reference only, please check.) |
14.3 Transport hazard class(es)
| ADR/RID: 6.1 (For reference only, please check.) | IMDG: 6.1 (For reference only, please check.) | IATA: 6.1 (For reference only, please check.) |
14.4 Packing group, if applicable
| ADR/RID: I (For reference only, please check.) | IMDG: I (For reference only, please check.) | IATA: I (For reference only, please check.) |
14.5 Environmental hazards
| ADR/RID: No | IMDG: No | IATA: No |
14.6 Special precautions for user
no data available
14.7 Transport in bulk according to IMO instruments
no data available
SECTION 15: Regulatory information
15.1 Safety, health and environmental regulations specific for the product in question
| Chemical name | Common names and synonyms | CAS number | EC number |
|---|---|---|---|
| 2-chloroethanol | 2-chloroethanol | 107-07-3 | 203-459-7 |
| European Inventory of Existing Commercial Chemical Substances (EINECS) | Listed. | ||
| EC Inventory | Listed. | ||
| United States Toxic Substances Control Act (TSCA) Inventory | Listed. | ||
| China Catalog of Hazardous chemicals 2015 | Listed. | ||
| New Zealand Inventory of Chemicals (NZIoC) | Listed. | ||
| Philippines Inventory of Chemicals and Chemical Substances (PICCS) | Listed. | ||
| Vietnam National Chemical Inventory | Listed. | ||
| Chinese Chemical Inventory of Existing Chemical Substances (China IECSC) | Listed. | ||
| Korea Existing Chemicals List (KECL) | Listed. | ||
SECTION 16: Other information
Information on revision
| Creation Date | July 15, 2019 |
|---|---|
| Revision Date | July 15, 2019 |
Abbreviations and acronyms
- CAS: Chemical Abstracts Service
- ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
- RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
- IMDG: International Maritime Dangerous Goods
- IATA: International Air Transportation Association
- TWA: Time Weighted Average
- STEL: Short term exposure limit
- LC50: Lethal Concentration 50%
- LD50: Lethal Dose 50%
- EC50: Effective Concentration 50%
References
- IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
- HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
- IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
- eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
- CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
- ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
- ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
- Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
- ECHA - European Chemicals Agency, website: https://echa.europa.eu/
Other Information
The occupational exposure limit value should not be exceeded during any part of the working exposure.Do NOT use in the vicinity of a fire or a hot surface, or during welding.
Any questions regarding this SDS, Please send your inquiry to sds@xixisys.com
Disclaimer: The above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any guarantee of the properties of the product. We as supplier shall not be held liable for any damage resulting from handling or from contact with the above product.